Effect of Supplementing Mouse Maternal Diet during Pregnant and Weaning Period by Fish Oil and Vitamin E on Male Offspring Reproductive Organs

The aim of this study was to investigate the effect of fed fish oil (FO) with or without vitamin E for mothers on the testis cells of male offsprings.
Sixty mature female NMRI mice were divided into different groups: control (CTR; Standard diet(vitamin E 50 mg IU/kg) pre and postnatal period); I) Gavages 0.01 ml/day/mother fish oil (FO)ऴ diet during prenatal period; II) Gavages FOऴ diet during postnatal period; III) consumed VITE(125 mg IU/kg) 2.5 folded greater than standard recommendations(2×)during prenatal period; IV)consumed VITE(2×)diet during pre and postnatal period; V)consumed VITE(2×)diet during postnatal period; VI) Gavages FO咄(2×) diet during prenatal period; VII) Gavage FO咄(2×)diet during postnatal period ;VIII) Gavages FO咄 (2×)diet during pre and postnatal period. After weaning, the testes were collected and histological data were analyzed using SAS software by Duncan test.
testes cells length, width and weight was lower in offspring which their mothers fed FOऴ diet during prenatal, (p The positive effects of supplementation maternal diet by FO with VITE or sole VITE was observed. Thus, antioxidants should be consumed along with omega-3 fatty acids in maternal diet.