The Comparative Study of Cardiopulmonary Effects of Intercostal and Intrapleural Injection of Bupivacaine after Thoracotomy in Rabbits

Bupivacaine is a medication used to decrease feeling in a specific area and it use in thoracotomy surgery. In this study two anesthesia methods, intercostal and intrapleural methods and that effects on respiratory and cardiovascular system were measured after injection of bupivacaine in thoracotomy surgery. 15 male New Zealand white rabbits aged 19 weeks with average 2 kg weight were divided into the three groups: control group did not receive a local anesthetic (A) and another two other groups, intercostal anesthesia (B) and intrapleural anesthesia (C). In all three groups, heart rate, respiratory rate, spo2 and Etco2 factors were examined in different times. Our results showed respiratory rate and heart rate in groups of B and C (intercostal and intrapleural analgesia) were less than group A that doesn’t received analgesic drug. We found that intrapleural method is effective than intercostal method and both of methods are better than control group.