Effect of hydro alcoholic Cinnamomum zeylanicum extract on leptine, triglyceride, total cholestrol levels and body weight in Male Wistar rats exposed to air pollution
Abstract:
Aim: Air pollution is a main problem in large cities˲it , s complicated problem and depend on many factors .Since air pollution is effective on the physical systems ˲especially the brain activity , metabolism and body weight˲ so the main aim of this study was to determine the effects of Cinnamomum zeylanicum on levels of leptin , triglyceride , total cholesterol and body weight in rats exposed to gasoline fumes .
Materials And Methods
In this study ˲36 male Wistar rats ˲weighting 200±20 were used.These animals were divided into 6 groups(n=6) including control , exposed to gasoline fumes and experimental groups treated with Cinnamon extract before and after exposure. They were tested three weeks.
Result
Data were statistically analyzed and compared between groups using ANOVA. Findings indicated that animals were exposed to pollution ,showed an increase in level of leptin ¡ triglyceride , total cholesterol compared with control group. After treatment with the extract (25mg/kg) , their levels decreased. The animals that received the extract twice a day could return the factors to normal levels than group which received the extract once a day .Body weight increased in control group but decreased in rats exposed to pollution, over a period of 21 days Cinnamon extract would return body weight to control levels in rats exposed to pollution .
Language:
Persian
Published:
Journal of Animan Researches, Volume:30 Issue: 1, 2017
Pages:
15 to 24
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