Effect of Colloidal Nanosilver Particles on Some of Liver Enzymes in Common Carp (Cyprinus carpio)

Inroduction & Despite increasing application of silver nanoparticles (NPs) in industry and consumer products, there is still little known about their potential toxicity, particularly to organisms in aquatic environments. Regarding fast development of the nanotechnology and its diverse applications, is very important having enough data on the probably its side effects on the aquatic body organs. Therefore, in this study the median lethal concentration “LC50” and the effects of nanosilver administration on the liver's biochemistry in cyprinus carpio
Material and Method For this purpose 84 fish were exposed to concentrations of(0.1, 0.5, 1, 2.5, 5, 10 ppm) for 96 hours and their mortality were recorded. By using probit analyses the LC50 was obtained 0.23 ppm. In next stage 84 fish in four treatment with three repeat in each treatment were exposed to (1/2 LC50, 1/5 LC50, 1/10 LC50) and contral treatment for 14 days. After 14 days 2 fish in each repeats was selected in random and were passed out with clove powder. Their livers were extracted. Then, Changes in AST,ALP,ALT levels were counted.
Results showed in AST,ALP,ALT levels a significant increase in the nanosilver treated fish (P