Comparing the Effects of the Platelet-Rich Plasma Gel with Wound Therapeutic Methods on the Treatment of Diabetic Foot
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background
The aim of this study was to evaluate the effects of platelet-rich plasma (PRP) gel on the diabetic wound in order to find a new safe and effective treatment method.
Methods
In this randomized clinical trial, 50 patients with diabetic wound were selected and randomly allocated into two groups. In the intervention group, 1 ml of platelet-rich plasma was administered topically at the wound edges, 3 times with one-week interval. The control group received routine treatment. Quality of life, pain score, wound extent, and incidence of infection were evaluated for all the patients within the first 3 months.
Findings: The mean score of quality of life after the first month in both groups was similar. However, the mean score of quality of life in the control group was lower than the intervention group after 2 and 3 months (31.88 ± 2.8 vs. 39.13 ± 1.35, respectively, P
Conclusion
Platelet-rich plasma gel seems to be effective in the treatment of diabetic foot. It is likely that this combination can be used as a treatment option in addition to standard treatment to be effective in controlling the wound and infection in short term. Considering the limitations of this study including small sample size, more studies are recommended.
Language:
Persian
Published:
Journal Of Isfahan Medical School, Volume:35 Issue: 450, 2017
Pages:
1389 to 1395
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