The Effect of Homograft Fillers on the Correction of Atrophic Scars

Atrophic scars and skin damage are of the problems in plastic surgery for which several treatment methods including dermofat and fat injections have been used so far; but the results vary and are sometimes contradictory. This study aimed to compare the effect of dermofat and fat injections on the treatment of atrophic scars.
In a clinical trial during 2015 and 2016 in Alzahra and Imam Musa Kazim hospitals, Isfahan, Iran, 50 patients with atrophic scars were distributed in two groups of 25 treating by fat and dermofat injection, respectively. The two groups were evaluated and compared 6 and 12 months after treatment and their scar condition, recovery, and complications were examined.
Findings: In dermofat graft and fat injection groups, 8 (32%) and 7 (28%) patients had a good recovery, and the condition of the scar on their skin resembled the skin of the adjacent area; but no significant difference was observed between the two groups (P = 0.760). The scar condition compared to before treatment and six months after the treatment in both groups was more favorable.
Both fat injection and dermofat graft have relative effectiveness in the treatment of atrophic scars and more studies are recommended.