Design and Synthesis of a New Colorimetric Sensor Based on Quinazolinone for Rapid and Highly Selective Recognition of Cu(II) Ion

In this study, a novel colorimetric chemosensor based on quinazolinone was designed and synthesized for the detection of Cu2 ions. The structure of synthesized chemosensor (C) was confirmed by Fourrier Transform Infrared (FT-IR), Proton Nuclear Magnetic Resonance (1H NMR) and Carbon Nuclear Magnetic Resonance (13C NMR) spectroscopies. The chemosensor C showed a high selectivity and sensitivity for the detection of Cu2 ion over the other tested anions and cations in acetonitrile-water solution. Interaction of C with Cu2 provides remarkable colorimetric change from colorless to yellow, enabling naked-eye detection without any spectroscopic instrumentation. Also, the sensing details were evaluated using UV-Vis spectroscopy. Furthermore, Job’s plot based on spectroscopic data showed one-to-one stoichiometry for the interaction of chemosensor of Cu2 cation with chemosensor C. Furthermore, the detection limit of chemosensor C towards Cu2 ions was found to be 67.5 μM.