Short-term effects of supplementation of coenzyme Q10 on humoral immune response to high intensity intermittent exercise in male soccer players

Current evidence suggests that coenzyme Q10 supplementation can play a role in enhancing immune function. Relatively, the aim of this study was to investigate the effect of 14-day supplementation of coenzyme Q10 on humoral immune response to intense exercise similar to soccer.
In this quasi-experimental study, 24 soccer players selected with a convenience sampling method and randomly divided into three equal groups (n=8): control, exercise and exercise with supplements Q10. Exercise includes three sessions of 90 minutes soccer specific training and supplementation includes intake of 5 mg/kg Coenzyme Q10 per day for two weeks. Blood samples within 24 hours before and after the intervention were collected from subjects.
The results showed that serum levels of cortisol and the percentage of Neutrophil in exercise group were significantly increased (P=0.001) while levels of IgA (P=0.008) and IgG (P=0.019) significantly decreased. However these changes in exercise and Q10 supplement group was not significant.
short-term supplementation of Coenzyme Q10 with the adjustment of immunoglobulin A and cortisol during strenuous exercise can improve the humoral immune function in soccer players