Comparison of the Effect of Melissa officinalis Capsule and Care Educational Programs on the Intensity of Physical, Mental and Social Symptoms of Premenstrual Syndrome in High School Female Students

Premenstrual syndrome (PMS) is one of the psychosomatic problems related to women›s reproductive function, which is associated with emotional and mood symptoms such as anger, anxiety and irritability. The current study aimed to compare the effect of Melissa officinalis capsule and care educational programs on the intensity of physical, mental and social aspects of PMS in high school girls.
This study was a randomized, placebo-controlled trial which was conducted on 200 high school girls with PMS who were randomly allocated into 4 groups in Shiraz. The first group received 600 mg of M. officinalis essence daily from the first to the end day of their menstrual cycle for 3 consecutive cycles; the second and third groups received care educational program and placebo respectively, and the last one was the control group. The data were analyzed using paired t test and Repeated measures analysis of variance (ANOVA).
The results of repeated measures ANOVA test revealed a significant reduction in 3 determined times, pre-intervention, one and 2 consecutive months after the intervention (P Melissa officinalis capsule and care educational programs were much more effective in reduction of the severity of physical, mental and social symptoms of PMS compared to the control and placebo groups.