The Effect of An Acute High Intensity Resistance Exercise on Blood Coagulation and Fibrinolysis Factors Pre-and Post 10 Weeks Resistance Training in Obese Children

The aim of this study was to evaluate the effect of an acute high intensity resistance exercise (AHIRE) on blood coagulation and fibrinolysis factors pre-and post 10 weeks resistance training in obese children. 30 obese children (8-12 yr) voluntary with body mass index 27.08±0.96 kg/m2 were divided into control and training groups. The resistance training consists of ten weeks (3 times per week) with the intensity of 40-60% 1 repetition maximum (1RM) for eight exercises. Acute high intensity resistance exercise includes 2 sets of 12 repetitions with 75%1-RM for eight exercises. Blood samples were taken 4 times before and after training period (before and immediately after acute exercise). The AHIRE causes increase in tPA and vWF and causes decrease in PAI-1. There were no signigicant changes in protein S, protein C levels, platelet count, aPPT and PT in response to AHIRE in control and training groups. D-dimer levels increased in respose to exercise in taining group only. Also, ten weeks resistnace training causes reduction in fibrinogen and IL-6 levels in response to AHIRE compared to the control group. Before resistance training the results suggested that changes in coagulation and fibrinolysis factors were similar in both control and training groups approximately, in response to AHIRE. But after adaptation to resistance training, the training group showed higher fibrinolysis factors and lower coagulation and inflammation factors in response to AHIRE, that was showed with elevation in tPA, D-dimer and vWF and reduction in IL-6 and fibrinogen levels.