Association Between the Platelet-to-Lymphocyte Ratio and the No-Reflow Phenomenon and Thrombolysis in Myocardial Infarction Flow 3 After Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction

Atherosclerosis is one of the major causes of cardiovascular mortality. Inflammation has been proven to have a role in this process, and inflammatory markers can predict the prognosis of atherosclerotic events such as acute coronary syndrome and ST-elevation myocardial infarction.
We sought to assess the prognostic value of the blood cell count and its components— platelets, C-reactive protein, cholesterol, triglycerides, creatinine, and troponin—in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention.
Significant prognostic values were found for the neutrophil count, platelet count, fasting blood sugar, cholesterol, triglycerides, low-density lipoprotein, creatinine, and C-reactive protein.
The platelet-to-lymphocyte ratio had prognostic value for predicting reflow after primary percutaneous coronary intervention. Nevertheless, C-reactive protein, platelet count, fasting blood sugar, cholesterol, triglycerides, low-density lipoprotein, and creatinine were more valuable in terms of predicting the outcome of percutaneous coronary intervention in patients with ST-elevation myocardial infarction. (Iranian Heart Journal 2017; 18(4):12-20)