Effect of the Lavender, sesame oil, combination of Lavender with sesame oil and silver sulfadiazine on the burn wound healing in mice

Message:
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background And Objective
Burn is one of the leading causes of mortality in the world. This study was done to determine the effect of the lavender, sesame oil, and combination of Lavender with sesame oil and silver sulfadiazine on the burn wound healing in mice.
Methods
In this experimental study, 30 male adult albino mice were randomly allocated into 5 groups as follows: the negative control group (physiology serum); the positive control group (silver sulfadiazine); the first experimental group (sesame oil), the second experimental group (combination of Lavender with sesame oil) and the third experimental group (Lavender oil).Second degree of burn wound healing take place using hot sheet with a diameter of 2 cm. wound treatment was done in five groups in 21-day treatment period. The wound diameter size and restoration percentage were measured on days 1, 3, 6, 9, 18, and 21. Some mice were euthanized and the samples of wounds were used for histopathological studies.
Results
The percentage of wound healing significantly increased in groups of silver sulfadiazine, combination of Lavender with sesame oil, Lavender oil and sesame oil in compared to control group (P
Conclusion
Combination of Lavender with sesame oil similar to silver sulfadiazine has tissue restoration effect on burn wound healing in animal model.
Language:
Persian
Published:
Journal of Gorgan University of Medical Sciences, Volume:20 Issue: 1, 2018
Pages:
51 to 57
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