Effect of Hyperlipidemia Patterns on Complete Blood Cell Count: A Case-Control Study
Author(s):
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background And Objective
Despite the speed and accuracy of cell counting devices in the analysis of blood samples, several confounding factors may influence their outcomes. This study was performed to assess the effect of hyperlipidemia patterns on the results of complete blood cell count (CBC).Materials And Methods
This analytical study (case-control) was performed among 306 non-diabetic and non-anemic patients, who were divided into five groups: 1) cholesterol above 200 mg/dl, 2) cholesterol above 200 mg/dl and low-density lipoprotein (LDL) over 130 mg/dl, 3) cholesterol 200 mg/dl and normal LDL, 4) triglycerides above 150 mg/dl, and 5) cholesterol above 200 mg/dl and triglycerides above 150 mg/dl. The blood cell count and indices were compared with the control group. After obtaining samples from the participants, the level of blood lipids and complete blood cell count were measured. Finally, statistical analysis and comparison between the two groups were performed with SPSS, version 20.Results
Comparison between the case and control groups separately in each of the five groups showed the following Results
1- White blood cell (WBC) and platelet count (PLT) in the group with high cholesterol level were significantly higher than the control group (PConclusion
Our study showed that hyperlipidemia patterns clearly increased blood cell count and indices. Therefore, hyperlipidemia patterns should be considered as a confounding factor in the interpretation of complete blood cell count.Keywords:
Language:
Persian
Published:
Avicenna Journal of Clinical Medicine, Volume:24 Issue: 4, 2018
Pages:
307 to 314
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