Post Exposure Effects of Propoxur (Agricultural Pesticide) on Male Fertility in Wistar Rat
Message:
Abstract:
Background
Pesticide toxicity is one of the major environmental health problems for the modern societies, as some of the effects may last long time after exposure. Propoxur is one of the Carbamate pesticide largely used in agriculture in the Western region of Cameroon.
Methods
In order to evaluate the post-exposure effects of propoxur, 48 male rats (12 animals per group) aged 30 d were orally gavaged with 0.00, 1.73, 2.60 and 5.20 mg.kg-1 body weight of propoxur for 90 d. At the end of treatment, 6 rats per group were sacrificed and others were followed up for 90 additional days and submitted to a fertility test before sacrifice.
Results
At the end of exposure propoxur significantly increased (P
Conclusion
Propoxur negatively affected male rats’ reproductive parameters with more significant adverse effects observed 90 d after the end of exposure.
Article Type:
Research/Original Article
Language:
English
Published:
Iranian Journal of Toxicology Scientific Quarterly Journal, Volume:12 Issue:3, 2018
Pages:
21 - 27
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