The adaptability of serum irisin, lipid profile, and insulin resistance to an aerobic exercise and the consumption of saffron and its sustainability in type 2 diabetic women

In order to study the beneficial role of aerobic activities and consumption of saffron which has various biological properties, the adaptability of serum irisin, lipid profiles and insulin resistance to an aerobic training and consumption of saffron sprouts as well as its sustainability in type 2 diabetic obese women was closely examined.
Forty-eight type 2 diabetic obese women were randomly divided into four equal groups (saffron training, training placebo, saffron, placebo). The saffron group training and training placebo groups did aerobic training with an intensity of 60-75% of maximal heart rate for 8 weeks (three sessions per week). A daily dose of 400 mg of saffron sprout powder (once a day) was used for two months. The placebo contained 400 mg of wheat flour. Then, the variables of irisin, lipid profiles, and HOMA-IR were investigated.
The results of this study showed that there were significant differences between training saffron group and training placebo, training saffron and saffron, training saffron and placebo, training placebo and placebo, and saffron and placebo (P Eight weeks of aerobic training and saffron consumption have a significant effect on the indices related to type 2 diabetes. It needs to be mentioned that the consumption of saffron along with aerobic exercise has more effects on controlling these indices.