Effects of vitamin D supplementation and resistance training on insulin resistance, lipid profile and body fat percentage in T2D men with vitamin D deficiency

The aim of this study was to investigate the effects of vitamin D supplementation during progressive resistance training on insulin resistance, blood lipids and body fat percentage in T2D men with vitamin D deficiency.
Forty-eight men with T2D participated in the study voluntarily and were randomly assigned to 4 groups (n=12) including, resistance training (RT), vitamin D supplementation with resistance training (RT), vitamin D supplementation (VD), and control groups (CON).The intervention lasted 12 weeks. VD group took 50000 IU of vitamin D supplements every two weeks, RT group performed resistance exercise 3 times /week, RT group received vitamin D supplements and performed resistance training, and CON group maintained normal daily life pattern. Body fat percentage, 25(OH) D, blood lipids, glucose and insulin were measured before and after the intervention. HOMA-IR was used to measure insulin resistance
There was a significant difference in HOMA-IR between the groups which had received vitamin D supplements (P It was concluded that use of vitamin D for 12 weeks during progressive resistance training would have positive effects on insulin resistance in T2D men with vitamin D deficiency. Vitamin D supplements can be used as an effective method to reduce diabetes symptoms.