Diagnosis of the disease using an ant colony gene selection method based on information gain ratio using fuzzy rough sets
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
With the advancement of metagenome data mining science has become focused on microarrays. Microarrays are datasets with a large number of genes that are usually irrelevant to the output class; hence, the process of gene selection or feature selection is essential. So, it follows that you can remove redundant genes and increase the speed and accuracy of classification. After applying the gene selection, the dataset is reduced and detection of differentially abundant genes facilitated with more accuracy. This will, in turn, increases the power of genes which are correctly detected statistically differentially abundant in two or more phenotypes. The method presented in this study is a two-stage method for functional analysis of metagenomes. The first stage uses a combination of the filter and wrapper gene selection method, which includes the ant colony algorithm and utilizes fuzzy rough sets to calculate the information gain ratio as an evaluation measure in the ant colony algorithm. The set of features from the first stage is used as input in the second stage, and then the negative binomial distribution is used to detect genes which are statistically differentially abundant in two or more phenotypes. Applying the proposed method on a microarray dataset it becomes clear that the proposed method increases the accuracy of the classifier and selects a subset of genes that have a minimum length and maximum accuracy.
Language:
English
Published:
Journal of Particle Science and Technology, Volume:3 Issue: 4, Autumn 2017
Pages:
175 to 186
magiran.com/p1836362  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 990,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
دسترسی سراسری کاربران دانشگاه پیام نور!
اعضای هیئت علمی و دانشجویان دانشگاه پیام نور در سراسر کشور، در صورت ثبت نام با ایمیل دانشگاهی، تا پایان فروردین ماه 1403 به مقالات سایت دسترسی خواهند داشت!
In order to view content subscription is required

Personal subscription
Subscribe magiran.com for 50 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!