The effect of cardiac rehabilitation on ApoA1 and ApoB in men with coronary heart disease (CHD) after coronary artery bypass graft (CABG)

Cardiac rehabilitation is a branch of rehabilitation medicine dealing with optimizing physical function in patients with atherosclerosis after coronary artery bypass graft (CABG). The aim of this study was to investigate the effects of a period of cardiac rehabilitation on serum levels of apo-A1 and apo-B in middle aged men with myocardial infarction after CABG.
Subjects were selected among middle aged men (50 to 60 years old) with CABG and assigned into two groups of control (n=10) and experimental (n=10). In experimental group, aerobic exercises (treadmill, cycle and hand ergometer) with the intensity of 11 to 13 on the (basis of burg scale) were performed during eight weeks under control of physician. Before and after the trainings, serum levels of ApoA1 and ApoB were measured by ELISA method.
Analysis of data using paired samples T test showed no changes in weight, BMI, levels of apo-A1 and apo-B and apo-B to apo-A1 ratio in control group (P>0.05), but in experimental group weight, BMI, apo-B and apo-B to apo-A1 ratio significantly decreased and apo-A1 increased (P Eight weeks cardiac rehabilitation, through reduction of apo-A1 and apo-B, can be effective in prevention of recurrent myocardial infarction and morbidity and mortality in middle aged men after CABG.