Evaluation of Early and Late Complications of Amniocentesis in Ommolbanin Hospital in Mashhad, Iran during 2014-2016

Amniocentesis is usually performed to genetically assess the fetus before birth. The most common complications associated with amniocentesis include the rupture of membrane (ROM), miscarriage, amniocentesis, as well as direct and indirect harm to fetus. The study aimed to evaluate the early and late complications of amniocentesis.
This cohort study was conducted on 1,000 pregnant women, who referred to the Perinatology Clinic of Ommolbanin Hospital in Mashhad, Iran during 2014-2016 to undergo amniocentesis by a perinatologist. To obtain 20 cc amniotic fluid, a needle was inserted into the gestational sac through the skin of the abdominal area of mothers using the ultrasound guidance. Subsequently, the researchers collected the data related to the early and late complications, pregnancy termination date, and neonatal complications through phone calls. Data analysis was performed in SPSS version 20 using Kolmogorov-Smirnov test.
From the evaluated neonates, 887 newborns (88.7%) were healthy. According to the results, spontaneous abortion, amniotic fluid leakage, spotting, amnionitis, and childbirth before 37 weeks of gestation were reported in 10 (1%), 16 (1.6%), 16 (1.6%), 2 (0.2%), and 173 (17.3%) of the cases, respectively. Furthermore, there were no reports of ocular, dermatologic and orthopedic complications in the study.
According to the results of the study, the most common early complications of amniocentesis were spotting and amniotic fluid leakage. Furthermore, preterm birth was the most common late complication of this procedure.