T3 and T4 changes study and its relation with Histopathology of thyroid glands in water buffalo in Ahvaz,IRAN

Thyroid hormons have an important role in regulation of metabolism of protein and energy metabolism in animals , particularly in ruminents.
In this study it was investigated the histopathology of thyroid glands and hormonal changes of T3 and T4 in water buffalo in Ahvaz, IRAN.
The thyroid gland tissues and blood samples were collected from 89 slaughtered buffaloes ( 66 females, 23 males). thyroid glands were selected and cut in to small pieces for standard histological processing, then the samples were stained with ( H & E) procedure and microscopically evaluated. Serum T3 and T4 concentration were measured by elisa methods. The data analyzed by the use of T- test.
The results showed that) 31% (of thyroid glands have pathological lesions. The lesions respectively includes; focal hyperplasia ( 31.5 %), metaplasia ( 2.2 %), and chronic thyroiditis ( 1.1%). Also the results showed that) 30.3%( female and )52.2 %( male buffaloes have pathological lesions.We found that T4 concentration of normal buffaloes without thyroid gland lesions was significantly higher than the other buffaloes ( P= 0.02).
This study showed that there was a positive and significant correlation between T3,T4 concenterations in buffaloes with thyroid gland lesions ( r = 0.4 , P0.05).