Evaluation of the infusion of magnesium sulfate on hemodynamic response after tracheal intubation in patients candidate for non obstetric gynecologic abdominal surgery

Tracheal intubation is an essential procedure during general anesthesia which may cons hemodynamic conditions to become unstable (high blood pressure, tachycardia increased pulmonary capillary wedge pressure & etc…) Magnesium sulfate could decrease catechol amine release from adrenal gland therefore could potentially decrease the side effects of tracheal intubation.
In this double blinded RCT, 50 patients candidate for non obstetric gynecologic abdominal surgery were randomly allocated into two groups of each 25 patients in case group, patients recieve 20mg/kg magnesium sulfate derag imin before infusion and control group recieve iv saline as some volume. Hemodynamic values were scored before induction and 1,5,10 and 15 minutes after intubation for all patients collected data were analyzed using SPSS ver. 18 and proper statistical tests.
Mean recovery time was 4f.92±6.7 min and 51.64±5.2 in control & case groups respectively study showed that mean hr before induction mean systolic BP before induction, on 1st minute and is minutes after intubation, mean diastolic BP in 1st minute, and mean arterial pressure (MAP) in all times except intubation time, mean spo2 in 5th minute and mean recovery time was statistically meaningful.
The mean of three values of systolic, diastolic & mean BP were statistically meaning in all times. Based on the findings of the study, low dose infusion of magnesium sulfate could increase cardiovascular response and recovery time after tracheal intubation