Effect of Gender Related Differences on Cerebral Oxygen Saturation

The present study was conducted to evaluate the cerebral oxygen saturation (rSO2) difference between female and male patients before induction of anesthesia and during anesthesia in neurosurgical procedures.
A total of 120 patients scheduled for elective neurosurgeries were enrolled in this prospective cohort study. SpO2, end tidal CO2 (EtCO2), and bilateral frontal rSO2 values were recorded during (1) the baseline (BL), (2) after raising FiO2, (3) after induction of anesthesia (Ind), (4) after tracheal intubation (after intub), (5) before positioning (pre-pos), and (6) after positioning for each patient at 1, 5, 15, 30, and 60 minutes after positioning.
A total of 111 patients were included for statistical analysis; of whom 59 were female and 52 were male. The mean age was 45.2 years for women and 47.7 years for men. Hemoglobin concentration was statistically lower in female patients. (12.5 ± 1.3 vs 13.6 ± 1.3, P value This study revealed that even after reducing the confounding role of hemoglobin, measured values of rSO2 were lower in the female group undergoing neurosurgical procedures.