The Controlled Comparison of Brain-behavioral Systems between Patients with Stabilized Methadone, Non-stabilized Methadone and Non-stabilized Methadone and other Drugs

The aim of this study was the comparison of the Gary-Wilson brain-behavioral (activation, inhibition and fight-/flight) systems between patients with diagnosed opioid use disorder on the methadone maintenance treatment (MMT). These are consisting in three groups: stabilized and non-stabilized including methadone or other drugs (except methadone) abusers.
This research was a comparative and statistical population has been all of the clients registered on Esfahan MMT caring units. Sample groups have included of the stabilized (60), non-stabilized methadone (57) and other-drug-abuser (57) individuals who answered to the related questionnaire. Statistical data has been analyzed by SPSS-18 through analysis of the Covariance (MANCOVA).
Findings: Analysis of the data showed that there were not significant differences in brain activation system, brain inhibition system and fight/flight system between three groups.
Despite of no significant difference of theses brain systems between three groups, but are differences between non-stabilized methadone groups in comparison to other two groups.