Effect of Endurance Training on Serum Levels of Alanine Aminotransferase, Aspartate Aminotransferase, and Resistin in Men with Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease is a public health problem in the world. Exercise is a first-line therapy for patients with non-alcoholic fatty liver disease. Therefore, the present study was conducted to determine the effect of eight weeks of endurance training on serum levels of alanine aminotransferase, aspartate aminotransferase, and resistin in men with non-alcoholic fatty liver disease. A total of 23 patients with non-alcoholic fatty liver disease were selected following purposeful sampling in the present quasiexperimental study. Participants were randomly divided into two groups: endurance training group (n=12) and control group (n=11). The endurance training program included moderate intensity training with 60-75% of maximal heart rate for 45 min/session, 3 times/week for 8 weeks. At both baseline and completion of the eighth week, blood samples were obtained from all the participants. Data were analyzed running Shapiro-Wilk test and dependent and independent t-tests at the significant level of p In the current study, eight weeks of endurance training resulted in a significant decrease in serum levels of alanine aminotransferase, aspartate aminotransferase, and resistin in males with non-alcoholic fatty liver(α<0.05). According to the findings, endurance training may improve the serum levels of alanine aminotransferase, aspartate aminotransferase, and resistin in men with non-alcoholic fatty liver disease. Therefore, to reduce the dependent risk factors of non-alcoholic fatty liver disease, this therapeutic intervention seems to be beneficial.