Investigating the bioavailability and antibacterial effect of silver nanoparticles produced by ( ferulago angulate Boiss.) extract

Silver nanoparticles have a wide range of aplications in medical sciences which their efects depend on their size. Synthesis of Silver nanoparticles is very valuable due to its numerous applications in detection of pathogens, cancer therapy and targeted drug delivery. The purpose of this research is to production of silver nanoparticles by using the aerial parts extract of Ferulago angulata extract and Check Antimicrobial activity of nanoparticles. Material and

To achieve this purpose, the obtained extract from Ferulago angulata Plant, was exposed to the silver nitrate solution of 0.1 molar with different concentrations for duration of 24,48, 72 and 96 hours. After changing the color to brown, by using UV-visible, DLS, SEM, TEM, XRD and FTIR analyses the existence of Nano silver particle was proved.

The UV-visible spectroscopy showed that silver nanoparticles had an absorption peak at 450 nm. By considering the results of conducted analyses, the mean diameter of particles was 19 nm and the size of particles about 3 to 62 nm and were spherical shape. Finally, the antimicrobial activity of silver nanoparticles against the Staphylococcus aureus, Bacillus cereus, Escherichia coli and Pseudomonas aeruginosa was investigated and proved.

The obtained results show the good functioning of this plant for the synthesis of nanoparticles clearly. So, It can be useful in the treatment of many diseases transmitted by the bacteria in the medical field