Systematic review and analysis of the effects of adaptation with aerobic and resistance training on blood flow-dependent dilation

The aim of this paper is to use a systematic review and meta-analysis to analyze the effectiveness of aerobic and resistance training on blood Flow mediated dilation In this study, flow mediated dilation was selected as valid index for vascular endothelial function. Search was done in databases PubMed, science direct, Scopus, Web of science, SID, Magiran and google Scholar with specified keywords among articles that were published in the years 1986 to 2016 both in Persian and English. After initial screening, full text search and critical appraisal, studies which pass the inclusion criteria were analyzed. From a total of 1562 articles that were analyzed, 23 received the study inclusion criteria for the systematic review. 14 study, which included 17 trials with meta-analysis inclusion criteria were analyzed. The results of the meta-analysis of studies showed that exercise can improve Flow mediated dilation in healthy subjects (SMD= 0/84, 95 % CI 0/55–1/13, p=0/001) and patients with coronary artery disease (SMD= 0/49, 95 % CI 0/30–0/68, p=0/001). Although the effect size obtained for different sports are different, but considering the low number of studies, we cannot make an absolute statement about the superiority of one method of training. The exercise can be effective in improving endothelial function, although still high-quality research studies with sufficient sample size is needed