Effect of One Supplementation Period of Methylsulfonylmethane and Glucosamine on Some Antioxidants Following a Plyometric Exercise Session

Intensive physical activity results in release of free radicals and oxidative damages in biomacromolecules. Consumption of sulfuric supplements may effect on the levels of oxidative stress following intensive exercises. Therefore, the effect of six weeks combined supplementation of methylsulfonylmethane and glucosamine on the glutathione peroxidase and catalase following a plyometric exercise session in amutor male athletes was studied in the present study. The study was a double-blinded quasi-experimental reseach with a pre- and post-test design in which 22 amateur male athletes (age mean: 26.18±4.02 years old; height: 176.00±4.10 cm; weight: 83.70±10.43 kg) were randomly assigned into two groups of supplement (n = 11) and placebo (n = 11), and participated in two bouts of plyometric exercise before and after the supplementation period. The supplementation period included daily consumption of 3 miligrams/bw combined methylsulfonylmethane and glucosamine for six weeks. The serum levels of Glutathione Peroxidase and Catalase enzymes were determined before and after the two plyometric exercise sessions, and the collected data were analyzed using analysis of covariance (ANCOVA) at p<0.05 significant level. After controlling the effects of the initial levels, the levels of glutathione peroxidase and catalase enzymes after exercise for the supplement group were higher than the placebo group (respectively, F2,9= 71.73, p=0.001 and F2,9= 191.76, p=0.001). Combined supplementation of methylsulfonylmethane and glucosamine may increase anti-oxidant capacity in athletes through increased levels of glutathione peroxidase and catalase enzymes