Association of Cord Blood Resistin with Neonatal Birth Weight and Gestational Age
ackground: Resistin is an adipocyte-secreted hormone with critical roles in energy, lipids, and glucose homeostasis. However, its specific role during fetal and neonatal period remains poorly understood.
This cross sectional study included 160 neonates in four groups of term-AGA, term-SGA, preterm-AGA, and preterm-SGA. Body measurements, blood sugar, and cord blood resistin were evaluated.
In SGA-preterm neonates: Resistin had reverse correlation with birth weight (P = 0.006) and positive correlation with gestational age (P = 0.002). In SGA-term ones resistin had positive correlation with gestational age (P = 0.041).
Cord blood resistin has a positive correlation with gestational age and a reverse association with neonatal birth weight. We suggest that these two different associations might be the cause of conflicting results in previous reports.
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