Effect of selenium difference sources on the blood parameters associated with the inflammation statues of fresh Holstein dairy cow

The transition period for a dairy cow is from 3 to 2 weeks prepartum until 2 to 3 weeks postpartum. Transition cow nutrition and management have received much attention in the research and popular-based literature in recent years because of the recognition of its importance in the productivity and health of cows. Also, Application of different source of minerals and their metabolism performance a current issue in animal science and research centers. The objective of this study was to selenium nanoparticles synthesis and investigate its effect compared with selenium source of sodium selenite on milk yield and composition and the blood parameters associated with inflammation and energy statues of Holstein dairy cow dairy cows. In this study 16 Holstein cows were selected (days in milk 5 ± 2) and assigned them randomly within one of the two experimental treatments in tie-stall pens for 35 days. These treatments were including: 1) diet with sodium selenite source (0.3 ppm sodium selenite), and 2) diet with selenium nanoparticles (0.3 ppm selenium nanoparticles). Milk yield and composition were measured for all cows. Blood parameters, including albumin, bilirubin, total cholesterol, beta hydroxide butyrate acid, non-esterified fatty acid, glucose, total protein, globulin and blood urea nitrogen, were collected at 3day intervals in 1, 14, 30 periods of experiment. Also, liver functionality index of cows was calculated. Except of milk protein percentage, no significant differences were observed in milk yield and composition. Milk protein percentage of cows was higher fed with diet with selenium nanoparticles compared to cows fed with sodium selenite diet (P-Value=0.05). There was no significant difference in plasma urea concentration between the two treatments in the present experiment. However, numerically plasma urea was lower in cows fed with diet with selenium nanoparticles compared to cows fed with sodium selenite diet. Statistically, blood plasma total protein of cows (P-Value=0.06) and globulin (P-Value=0.1) tended to significant. There was no significant difference in blood parameters related to liver function among experimental treatments. As there was no significant difference in serum cholesterol, bilirubin and albumin in blood plasma in cows fed from diet with sodium selenite compared to cows fed from diets with selenium nanoparticles. When the values of these parameters were placed in the formula of the liver functionality index. The results of the present experiment showed that diet with selenium nanoparticles had a positive effect on milk protein. Also, a glance at the results of blood parameters revealed no significant differences in blood parameters of cows fed selenium with nanoparticles or sodium selenite source. It seems, due to experience the metabolic complexity of dairy cows during the transition and fresh periods, judgment must be thinkable in order that nanoparticles can have a positive or negative effect on the metabolic function and ultimately the production performance, and it is necessary to study further studies on the nutrition of selenium nanoparticles in dairy cows.