Comparison of the Effect Menstrugloe Capsule and Vitamin E on the Intensity of Primary Dysmenorrhea Based on Multi-dimensional Speech Scale

Primary dysmenorrhea is one of the common disorders of the reproductive system. Various methods are suggested for treatment of dysmenorrhea. This study was performed with aim to determine the effect of Menstrugloe capsule and Vitamin E on the intensity of primary dysmenorrhea. This double-blinded randomized clinical trial was performed in 2017 on 120 female students with primary dysmenorrhea at Hamadan University of Medical Sciences. The samples were randomly divided in three 40-member groups. The first group received 500 mg Menstrugole capsules, second group 200 mg Vitamin E, and third group placebo capsule every 8 hours, from the first day of starting pain for 3 days during two menstrual cycles. The intensity and duration of dysmenorrhea in each cycle was compared by multidimensional speech scale and McGill pain scale. Data was analyzed by SPSS software (version 21) and Chi-square, paired t-test, and ANOVA. P<0.05 was considered statistically significant. Before the intervention, the mean scores of duration and severity of symptoms of dysmenorrhea was homogenous in the groups, but after the intervention, according to ANOVA test, there was significant difference between the subjects (P<0.001) and it was less in the Menstrugole group. According to Chi-square test, after the intervention, the severity of dysmenorrhea based on McGill pain scale was significantly different in the three groups (P<0.001) and it was less in the Menstrugole group. The use of Menstrugloe capsule like vitamin E can reduce the intensity of primary dysmenorrhea; therefore, due to limited side effects, it can be useful in women with dysmenorrhea.