THE EFFECT OF 12 WEEKS OF HIGH INTENSITY TRAINING ON IL-6, GLP-1 AND LIPID PROFILES IN TYPE 2 DIABETIC PATIENTS

The aim of this study was to investigate the effect of 12 weeks of high intensity training on IL-
6, GLP-1 and lipid profiles in type 2 diabetic patients 80 participants (40-50 years old) volunteered to participate in the study and divided into eight groups (four groups of severe periodic exercises and four uncontrolled control groups). Blood samples were collected and analyzed for measuring IL-6, GLP-1, lipid profile and glycemic index before and after weeks 4, 8 and after the training program. After 12 weeks of training, the effect of time and interaction between time × group on GLP-1 and IL-6 variables was statistically significant. Also, there was a significant difference between groups based on 12 weeks of training in these indices. Lipid profile was significantly improved in type 2 diabetic and glycemic control in obese and non-diabetic groups that had 12 weeks of high intensity interval training. Overall, high intensity interval training, through changes in various mechanisms, lead to improvement in lipid and glycemic disorders, inflammation and appetite in obese people with type 2 diabetes. Hence, according to the findings of the study, researchers suggest that performing high intensity interval training can lead to significant improvements in obese subjects (with and without type 2 diabetes).