Effect of a single session high intense interval exercise in hypoxic and normoxic conditions on serum concentration of interleukin-6 and 10 in active men

exercise induces considerable physiological change in the immune system. The aim of this study was to investigate the effect of a single session high intense interval exercise (HIIE) in hypoxic and normoxic conditions on serum concentration of interleukin-6 (IL-6) and interleukin-10 (IL-10) in active men. The present study was semi experimental research Ten trained students volunteer in shahid Beheshti University participated in this study. General and clinical information was collected via questionnaire before exercise began. In addition some of body composition indexes of subjects were measured one day before exercise protocol. After determining maximum heart rate of subjects during HIIE which was consisted of three series, each series consisting of three one-minute repetitions with intensity of 80 to 85 percent of maximum heart rate and 2 minute rest between series in both hypoxic and normoxic conditions performed one week apart. Before, immediately after, and 1 h after exercise blood samples were taken from subjects. To measure IL-6 and IL-10 Elisa method was used. Finding showed that despite a significant increase in serum levels IL-6 due to HIIE between the two conditions did not differ significantly (p = 0.078). But with increased serum levels of IL-10 in HIIE there was significant difference between the two conditions (p = 0.003). The short-term exercise under hypoxic conditions with the appropriate intensity could modify the immune system response and increased levels of IL-10.