Effect of interaction between resistance training and fasting on removal of creatinine and glomerular filtration in sedentary women with abdominal obesity

Abdominal obesity is associated with the risk of albumin increasing which is the main reason for decreasing in renal function. The aim of this study was to investigate the interaction between resistance training (RT) and fasting on the removal of creatinine and glomerular filtration in sedentary women with abdominal obesity. In this semi-experimental study, 60 sedentary women (average age: 38.3±5.2 years) participated in four groups of 15 persons –including RT, RT with fasting, fasting, and control (no fasting and no exercise). During Ramadan, the RT program consisted of eight main exercises with moderate intensity was performed with emphasis on large muscles for 3 times per week. The fasting duration in Ramadan was about 17 hours. Bio-impedance technique for the assessments of creatinine and glomerular filtration rate were used. Data were analyzed by one-way ANOVA, Bonferroni post hoc, and Pearson correlation coefficient tests. One-way ANOVA results showed that the creatinine clearance (p=0.048) and glomerular filtration (p=0.049) in fasting group were significantly higher than the control group, but no significant difference was observed among other groups. Pearson correlation coefficient showed that creatinine clearance and glomerular filtration rate had an inverse and significant relation with age, while these variables were directly correlated with body mass index. According to the findings of this study, it seems that 17 hours of fasting may have a positive effect on the renal function in women with abdominal obesity.