The Effect of 8-week Aerobic Exercise with Spirulina Supplementation Consumption on Plasma levels of MDA, SOD and TAC in Men with Type 2 Diabetes

Influence of physical activity with supplement consumption on the decrease of free radicals effects is not well known during exercise. Spirulina(Herbal Supplement green algae – blue) is one of the richest sources of Protein and antioxidants. Thus, the purpose of this study was to investigate the effect of 8-week exercise with Spirulina consumption on peroxidant and antioxidants indicators (TAC, SOD, MDA) in men with type 2 diabetes. 32 sedentary men with type 2 diabetes participated in this study with average age of 40 years and with no history of regular exercise that were randomly divided into 4 groups: control (C), exercise (E), supplementation (S) and exercise + supplementation (E+S). Training programs were 45 minutes of aerobic exercise, 3 times in week with 60-65% of maximal heart rate. S and E+S groups consumed Daily 2 tablets of 500 mg Spirulina. Blood samples were taken in two phases (before and after 8 weeks) following 10 to 12 hours of being fasted. Results showed MDA decreased significantly, but SOD and CAT levels increased significantly in E, S, E+S groups after 8 weeks (P ≤ 0/05). Also there was a significant difference between MDA in E and E+S groups after 8 weeks (P ≤ 0/05).The results showed that regular aerobic exercise with Spirulina consumption can improve peroxidant and antioxidant balance in men with type 2 diabetes and prevent exercise-induced oxidative stress and also diabetes.