Effect of Different Levels of Nanoparticle Curcumin on Egg Quality, Blood Parameters, Immune Response and Digestibility in Laying Hens

This study was conducted to investigate the effect of different levels of dietary nanoparticels curcumin on egg quality, serum biochemical, immune response and digestibility of laying hens. A total of 160 laying hens (Hy-line w-36) at 60 weeks of ages, were used in a completely randomized design, with four treatments and four replicates and 10 hens each. Dietary treatments were a basal diet without nano curcumin (control) and diets containing 400, 800 and 1200 mg nanomicelles curcumin per kg of diet. Egg quality and quantity variables were measured bi-weekly. The serum biochemical parameters were measured in the middle and at the end of experiment. In sixth week of trail, SRBC was injected to breast muscle and then serum immunological factors were mausured at seven and eight of weeks. Addition of nano curcumin had no effect on shell thickness, but in the final weeks of experiments nono curcumin showed significant effect on yolk color. It was revealed that ALT and AST concentration were significantly affected (P<0.05) by the nano curcumin dosages. At the end of experiment, cholesterol and LDL concentrations and HDL: LDL ratio was affected by consuming levels (P<0.05). 400 mg of nano curcumin showed the best immune response compared to control group. The highest amount of absorption was revealed in 800 and 1200 mg nanoparticles. Low levels of nano curcumin (400 mg) showed the positive and consistent effects on serum biochemical and immunological parameters, Curcumin digestibility and also yolk color.