Effect of 8-week Swimming training and garlic intake on serum ICAM and VCAM adhesion molecules in male obese rats

 Swimming training and garlic intake can be a preventing factor in coronary artery disease. Therefore, the aim of this study was to examine eight swimming exercises and garlic consumption on serum intercellular cell adhesion molecule (ICAM) and vascular cell adhesion molecule (VCAM) values in obese male rats. In this experimental study, 28 male Wistar rats (mean weight 281 ± 5.9 gr) were randomly divided into four groups (control, garlic supplementation, swimming training,swimming training + garlic supplementation). Then, the training group received training sessions for 8 weeks, 3 sessions per week, and the supplemented groups + supplementary supplement received 1 ml of garlic solution per kilogram of body weight per day. Data were analyzed using one-way analysis of variance and significant level (P ≤ 0.05). The findings showed that eight week training and intake garlic on the ICAM values of the rats significantly decreased. (P <0.05). However, there was no significant effect on the VCAM values of the male rats (P <0.05). It seems that the combination of two factors of swimming training and supplementation of garlic extract or exercise alone leads to a reduction in the levels of adhesive molecules and it is recommended to use it. However, in order to determine its impact, we need more research in human samples.