Food Components with Anti-Helicobacter Pylori Aactivities.

Helicobacter pylori (HP) infection which has been reported prevalent in developing countries is known as the major cause of most types of gastritis, gastric ulcers and gastric cancer. Although the eradication of this infection is considered as one of the health priorities, the antibiotic resistance impedes routine treatment in many cases. Several preclinical studies have demonstrated the efficiency of some natural products against H. pylori infection. These results may be rejected or confirmed in humans. Our purpose is to review the food items that have been tested against HP infection in clinical trials. We searched for related articles in scientific databases (Google scholar, PubMed, Science Direct and SID) using related keywords without Custom date range. Probiotics, lactoferrin of milk, black seed and products of maillard reaction probably increase the eradication rate and reduce the medication induced side-effects such as nausea, diarrhea and abdominal pain. Also medium or short-acting anti-HP effect of virgin olive oil, broccoli and cranberry, are reported too. Utilizing anti-bacterial natural ingredients seems to improve the impression of medicinal therapy. In order to accurately determine the effective dose and preparation of the mentioned natural products further clinical trials are needed.