Bacterial resistance to antibiotics is a serious threat to human health. According to increasing
of bacterial resistance to current antibiotics and their side effects, study of medicinal plants to use in treatment
is necessary. In the present study, the antimicrobial effects of honey also essential oil and extracts of Thymus
daenensis, which is an Iranian native species was examined. In this study,the antimicrobial effects was examined on standard strains of Staphyloccus
aureus, Pseudomonas aueroginosa and Escherichia coli. The effects of honey,extracts and essential oil against
bactria was assessed by agar well diffusion, Disc diffusion and Dilution test methods. The results showed that studied honey has low antimicrobial effect on these bacteria, in tested
concentrations of essential oil, S.aureus were showed more sensitivity. As well as aqueous extract hadn’t effect
on E.coli and Ps.aueroginosa and in concentrations of alcoholic extract S.aureus were showed more sensitivity. According to antimicrobial effects of honey and Thymus daenensis, studies on antimicrobial
effect for clinical application in treatment of infections is necessary.