Comparison of the effect of Chlorhexidine mouthwash with Green tea(Dine) mouthwash on probable ventilator-associated pneumonia in pediatric intensive care unit

Abstract Introduction The use of mouthwashes has recently been effective in reducing ventilator-associated pneumonia in patients admitted to ICU. However, in this study, the effect of chlorhexidine mouthwash with Green tea mouthwash was compared on prevention of ventilator-associated pneumonia in the patients in PICU of Imam Hossein Hospital in 1395-1396. Methods  In this clinical trial study, 80 patients admitted to PICU were enrolled according to the study and then the patients were divided into two group under treatment with 0.2% chlorhexidine gluconate and green tea  mouthwash. The frequency, time, and manner of mouthwash in both groups were performed in one form three times a day , every eight hours , for 5 days . The incidence of pneumonia and mortality were studied in patients after drug use . Results  The incidence of pneumonia was 10% in the chlorhexidine group and 12.5% in the green tea group, so there was no significant difference between  two groups based on the incidence of pneumonia (P = 0.72). The results of the treatment in the chlorhexidine group were : 65% complete recovery, 22.5% recovery with complication and 12.5% death, and Green tea were : 57.5% complete recovery, 35% recovery with complication and 7.5% death, and the difference between two groups was not significant (P = 0.43). Conclusion  Both chlorhexidine and dine mouthwash can be effective in reducing the incidence of ventilator associated pneumonia and mortality in patients, admitted in  ICU.