Antimicrobial and Healing EffectBurdock and Nasturtium of Nettle, Extracts With Silver Sulfadiazine on Burn Infections of Staphylococcus aurous
Inroduction & Objective: Staphylococcus aurous causes a wide range of diseases. Staphylococcal infection is the most common bacterial infection in humans. Antimicrobial and healing effect burdock and nasturtium of nettle, extracts with silver sulfadiazine on burn infections of Staphylococcus aurous. Material and Method: In this study, aqueous and ethanolic extracts of nettle, watercress and burdock root were prepared in the laboratory. Then, the MIC and MBC of the extract were determined by dilution method in the broth. In the study of the animal model, the bacteria were first inoculated with a concentration of (5×106CFU/ML) to the wound site on Syrian mice. After 24 hours, an ointment prepared with MBC concentration was prepared from extracts of the nettle, watercress and burdock root for 1 g of silver sulfadiazine and was used to treat burns and infections with Staphylococcus aurous. In the animal model, the aqueous and ethanolic extracts of nettle, watercress and burdock root have antimicrobial activity against growth of Staphylococcus aurous. Results: In this study, aqueous and ethanolic extracts of nettle, watercress and burdock root were prepared in the laboratory. Then, the MIC and MBC of the extract were determined by dilution method in the broth. In the study of the animal model, the bacteria were first inoculated with a concentration of (5×106CFU/ML) to the wound site on Syrian mice. After 24 hours, an ointment prepared with MBC concentration was prepared from extracts of the nettle, watercress and burdock root for 1 g of silver sulfadiazine and was used to treat burns and infections with Staphylococcus aurous. In the animal model, the aqueous and ethanolic extracts of nettle, watercress and burdock root have antimicrobial activity against growth of Staphylococcus aurous. Conclusion: According to the findings of this study, it can be concluded that the extract of these three plants (nettle, watercress and burdock root) on an animal model has antimicrobial and healing effects on Staphylococcus aurous. It can be used as an anti-inflammatory agent or ointment Bacteria to be raised. In this case, the extract of nettle and burdock root have growth inhibitory and bactericidal activity stronger than watercress extract. And it is hoped that in the future, these plants will be used to treat bacterial infections
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