Relationship of Serum Lipid Levels and Other Underlying Factors With Cognitive Impairment in the Elderly
Message:
Abstract:
Objectives
 The involvement of factors such as serum lipids and lipoproteins concentration has been reported as a potential risk factor for cognitive impairment. This study aimed to investigate the effect of underlying factors and serum lipid levels on cognitive impairment in the elderly.
Methods & Materials
 This cross-sectional study was conducted on 1519 elderly in Amirkola City by the census method, from September 2016 to March 2017 (6 months). The data collection tools were a background information form of older adults and the mini-mental state exam. The obtained data were analyzed in SPSS version 23 using descriptive statistics and inferential statistics such as the Kolmogorov-Smirnov test, the Chi-squared test, analysis of variance (1-way ANOVA) and Tukey’s post hoc test.
Results
 According to the results, 9% (13 elderly) of the study population had severe cognitive impairment. The results of the Chi-square test did not show a significant relationship between gender and cognitive impairment (P>0.05). The significant differences were found between age, blood pressure, total cholesterol, and low-density lipoproteins variables with the categorized groups of cognitive impairments of the elderly (P≤0.05). 
Conclusion
 Screening for cognitive impairments is one of the recommendations of this study. Early diagnosis and treatment of this disease, especially in high-risk groups such as women and elderly with hypertension and disrupted serum lipid profile can play an important role in controlling the disease and reducing the care burden.
Article Type:
Research/Original Article
Language:
English
Published:
Iranian Journal of Ageing, Volume:13 Issue:52, 2019
Pages:
534 - 548
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