Comparison of the diffrent clustering methods for population structure of Sarabi and Nadjdi cows by using dense genetic markers

Article Type:
Research/Original Article (دارای رتبه معتبر)
 So far, various methods have been used to investigate the structure of the population using the markers available in the whole genome (single-nucleotide polymorphism (SNP)), each of which has Weakness and strength. In the present study, an unsupervised network clustering (SPC), a data-mining method, was used to survey the population structure of the Sarabi and Najdi cows.
Materials and methods
The study population 424 cattle consisted of 213sarabi cattle and 211 Najdi cattle, sequenced with Illumina Bead Chip 40 K v 2 for single nucleotide markers. SORTING POINTS INTO NEIGHBORHOOD(SPIN) was used to analyze population structure. After editing data, 27859 autosomal markers were analyzed.
Clustering results based on the similarities and differences between nucleotides led to the classification of two base populations and nine clusters.
Comparison the number of samples and other existing methods for population layering, the use of the SPIN method with high computational efficiency and the needn`t for prior assumptions makes it possible to analyze the structure of populations.

Journal of Agricultural Biotechnology, Volume:11 Issue: 1, 2019
25 to 54  
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