Prevalence of Left Ventricular Dyssynchrony in Individuals Undergoing Gated SPECT Myocardial Perfusion Imaging Using Phase Analysis
Author(s):
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Left ventricular (LV) synchrony is a clear indicator of cardiac performance. However, left ventricular dyssynchrony (LVD) is not necessarily a sign of heart malfunction. Individuals at a higher risk of developing heart failure can be identified by LVD. Gated SPECT myocardial perfusion imaging (MPI) allows the simultaneous assessment of LV perfusion, function, and mechanical dyssynchrony through phase analysis. The aim of this study was to evaluate the prevalence and predictors of LVD in patients undergoing MPI. A total of 907 consecutive patients referred to the Nuclear Medicine Department of Farshchian Heart Center, Hamadan, Iran, for diagnostic purposes were examined. The patients underwent gated SPECT MPI with a 2-day stress/rest protocol. Auto-Quant software package was used to evaluate perfusion, function, and phase analysis. Additionally, significant LVD was assessed based on the following criteria: standard deviation of the LV phase distribution > 19.6 and a phase histogram > 72.5 in the stress phase of the examination. Several variables were evaluated using univariate and multivariate analyses. The variables significantly associated with LVD were sex (male), obesity, hypertension, diabetes, QRS > 120 ms, a history of coronary artery disease, myocardial perfusion defects reported on MPI, and LV dysfunction. Our results suggested that the prevalence of significant LVD as a predictor of adverse cardiovascular events, death, and progression to heart failure was 12.9%. The multivariate analysis revealed that variables such as obesity, diabetes, hypertension, sex (male), coronary artery disease, and QRS >120 ms were highly associated with LVD.
Keywords:
Language:
English
Published:
Iranian Heart Journal, Volume:20 Issue: 3, Fall 2019
Pages:
66 to 74
magiran.com/p2003791
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!