Review of Geant4 Applications in Radiobiology
Message:
Abstract:
Introduction
Ionizing radiation is widely used in industry and medicine; however, it causes a significant health hazard by making microscopic damage to living tissue. Various biological parameters, including cell survival fraction and relative biological effectiveness, are taken into account to assess the severity and extent of biological damages. Microdosimetry suffers from various shortcomings and limitations, but the development of some powerful simulation software has paved the way to resolve these problems in recent years.
Material and Methods
In this study, the authors were looked for two keywords (Geant4 and radiobiology) in the title, abstracts, and keywords of Scopus and PubMed database articles.
Results
More than 100 articles were found. The researchers extracted the articles that were devoted to the construction of different geometries for DNA, nucleus, and cells as simulate the parameters, such as relative biological effectiveness, SF, linear energy transfer, and single-strand breaks/double-strand breaks in the present study.
Conclusion
Geant4 is one of the software commonly used to simulate biological factors. It has many properties, such as the ability to follow up physical processes in very low energy, open source code, and flexibility in complex geometries. In this paper, we reviewed some of the radiobiological parameters simulated with Geant4.
Article Type:
Research/Original Article
Language:
English
Published:
Iranian Journal of Medical Physics, Volume:16 Issue:4, 2019
Pages:
255 - 263
magiran.com/p2004478  
روش‌های دسترسی به متن این مطلب
اشتراک شخصی
در سایت عضو شوید و هزینه اشتراک یک‌ساله سایت به مبلغ 300,000ريال را پرداخت کنید. همزمان با برقراری دوره اشتراک بسته دانلود 100 مطلب نیز برای شما فعال خواهد شد!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی همه کاربران به متن مطالب خریداری نمایند!