Morbidity and mortality of infections in the cirrhotic patients: a US population-based study
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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Aim
This study aims to investigate the morbidity, mortality, and health care utilization of infection in patients with cirrhosis, with the hope of making clinical recommendations.
Background
The pathophysiology of liver cirrhosis makes patients susceptible to a variety of complications including infection. It contributes to a staggering rate of death and places a tremendous financial burden on the health care system.
Methods
The pathophysiology of liver cirrhosis makes patients susceptible to a variety of complications including infection. It contributes to a staggering rate of death and places a tremendous financial burden on the health care system.
Results
In this cross-sectional study, we queried the National Inpatient Sample (NIS) database for patients discharged from United States (US) hospitals with International classification of diseases (ICD) diagnostic codes consistent with liver cirrhosis, between January 2011 and December 2014. The patients were classified based upon the presence or absence of an infection, as well as their demographics and comorbidities. The data was then analyzed using the IBM SPSS version 25 statistical software.
Conclusion
From 2011 to 2014, 660,727 cirrhotic patients were identified. Of these, 20.6% were found to have an infection. The mortality rate during hospitalization was 4.7% of all cirrhotic patients. The hospital length of stay was significantly longer for the study group than the control group (8.22 days versus 5.11 days) (P <0.0001). Similarly, the mean hospital cost was higher in the study group compared to the control group ($74,729.53 ± $125,963.75 vs. $46,413.32 ± $71,936.50 P< 0.0001).Keywords: Liver Cirrhosis, infection, morbidity, mortality, hospital costs.(Please cite as: Saleem S, Katragadda R, Weissman S, Bleibel W. Comparison of ISG15, IL28B and USP18 mRNA levels in peripheral blood mononuclear cells of chronic hepatitis B virus infected patients and healthy individuals Morbidity and mortality of infections in the cirrhotic patients: a US population-based study. Gastroenterol Hepatol Bed Bench 2019;12(3):233-238).
Language:
English
Published:
Gastroenterology and Hepatology From Bed to Bench Journal, Volume:12 Issue: 3, Summer 2019
Pages:
233 to 238
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