Antimicrobial Activity of Platelet-Rich Plasma and Platelet-Rich Fibrin Against Streptococcos Oralis

In recent years, the regenerative potential of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) have been studied in various fields of medicine. The purpose of this study was to investigate the antimicrobial activity of PRP and PRF against Streptococcus Oralis. In this in vitro study, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against this organism were determined by microdilution broth in visual method and turbidity by ELISA reader. The assay was done in triplicate. The results were analyzed using analysis of variance (ANOVA) test. Comparison of MIC at various concentrations of the solution showed that there was a significant difference between MIC of PRP and PRF. Moreover, the results showed that PRP and PRF solutions have not led to a complete halt in bacterial growth (MBC). PRF in comparison to PRP results increased the inhibition of bacterial growth and is recommended for use in the treatment of most studies.