Multifocal Extramedullary and Multiple Solitary Bone Plasmacytoma: A Case Report and Review of the Literature

Solitary bone plasmacytoma and extramedullary plasmacytoma are the proliferation of plasma cells in bone or soft tissues, without bone marrow involvement or other systemic presentation of multiple myeloma. A separate category of plasmacytomas is identified that “occur as multiple sites of disease in soft tissue, bone, or both soft tissue and bone”. Multiple extramedullary plasmacytoma or multiple solitary plasmacytoma is defined as when there is more than one extramedullary tumor of plasma cells or multiple sites of disease in bone. We report such rare case of multiple extramedullary plasmacytoma involving skin and soft tissues of abdomen wall, pelvic, chest, and solitary plasmacytoma bone in rib 6 chest and in bone of sacrum also diagnostic work up, treatment and care to the patients we have done. Prognosis is very poor, and if it is appropriate to stem cell, transplantation is considered to prevent recurrence