The predatory bugs, Anthocoridae, are important predators of many agricultural pests in the world. Climate and agricultural manipulations may change pest populations by affecting biodiversity of biocontrol agents. In this study, fauna and biodiversity of the Anthocoridae family were investigated in two climates of Hormozgan province: Tazian and Minab. The effect of agricultural manipulations on the anthocorid biodiversity was also determined. Sampling was carried out on various annual and perennial plants in both non-manipulated and manipulated (cropping and horticultural systems) ecosystems. Data were analyzed by SDR software according to various diversity and evenness indices. Five species from genus Orius, Orius (Dimorphella) albidipennis (Reuter1884), O.(Dimorphella) maxidentex (Ghauri, 1972), O. minutus (Linnaeus‚ 1758), O. laevigatus (Fiber‚ 1860) and O.niger (Wolff, 1811), and three species, O. albidipennis, O. maxidentex and O. minutus, were collected from various host plants of Tazian and Minab climates, respectively. Biodiversity and species evenness index values in Tazian were significantly higher than Minab. The highest and lowest biodiversity index values were observed in spring and fall, respectively. The evenness index values were significantly higher in winter and spring than summer and fall. However, no significant difference between biodiversity of manipulated and non-manipulated ecosystems was found in each climate. Dominant species were different according to climate condition. Moreover, our findings indicated that climate and season significantly affect biodiversity of anthocoridbugs.  Agricultural manipulation had no significant effect on the biodiversity of anthocorid bugs. The results can be used in biological control program of various pests by these predators in Hormozgan province.