Different concentrations of Vertimec in the gastrointestinal tissue of common carp (Cyprinus carpio) fed isomaltooligosaccharide

In this study, 147 common carp for two weeks were kept in the aquarium condition. LC50 / 96h of Vertimec was calculated as 1.243 and on this bais three lethal concentration 2, 3, 6 ppm were considered for this study. Isomaltooligosaccharide prebiotic was spereyed to the food as 1 g / kg. The results showed that after induction of isomaltooligosaccharide to the treatments that were exposed to vertimec, histopathological disorders such as vacuolization latest, bleeding, necrose, degeneration of the epithelium, loss of intestinal villi in the intestinal tissue was observed.  Concentration of 6, 3 and 2 ppm had severe effects on intestinal tissue, respectively. Isomaltooligosaccharide could not decrease the histopathological effects tissue due to vertimec exposue. Since tis prebiotic is absorbed via intestinal tissue and can show its positive effect of this organ, but the results did not show significant and positive effect in the intestinal tissue.