The effect of 8 weeks of HICT training on serum levels of catalase, malondialdehyde and maximal oxygen consumption in breast cancer survivors: Randomized clinical trial

Women with breast cancer do not have a desirable antioxidant defense system, especially catalase, lipid oxidation and aerobic power. Considering the effect of exercise training on these factors, the present study aimed to investigate the effect of eight weeks of high intensity circuit training on serum levels of catalase and malondialdehyde, and the aerobic power in breast cancer survivors.

In this semi-experimental study, 17 women rescued from breast cancer volunteered and randomly divided into two groups of exercise (n=9) and control (n=8). Subjects participated in an 8-week HICT protocol that performed 3 sessions per week. 24 hours before and 48 hours after the training protocol, the fasting blood sample was taken by the laboratory expert between 7:30 minutes to 8 hours. Serum levels of catalase and malondialdehyde, and maximum oxygen consumption were measured. The analysis of covariance was used to identify any significant differences and statistical significance was set at P<0.05.

The results showed that Waist-to-hip ratio (WHR) (P=0.90), weight (P=0.284) and malondialdehyde (P=0.154) had a non-significant difference and in the variables of Vo2max (P=0.0005) and catalase (P=0.036) there is a significant difference between the two groups.

It is suggested that short-term and effective exercise training such as HICT training, should be used with a view to facilitating and beneficial effects for women with breast cancer in order to reduce oxidative stress and improve aerobic capacity as a non-pharmacological supplement.